Spatial atlas of diabetic kidney disease reveals a B cell-rich subgroup

Sample acquisition and ethics approval The University of Pennsylvania institutional review board (IRB) approved the collection of human kidney tissue for this study. Left-over kidney samples were irreversibly de-identified, and no personal identifiers were gathered. Therefore, they were exempt from IRB review (category 4). We engaged an external, honest broker who was responsible for clinical data collection without disclosing personally identifiable information. …