Base editing reveals an essential role for NANOG in human embryogenesis

Loke Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK Oliver J. Bower, Ana E. R. Orsi, Riley McMahon, Desislava Staneva, Josephine Blagrove, Claire S. Simon, Katarina Harasimov & Kathy K. Niakan Human Embryo and Stem Cell Laboratory, The Francis Crick Institute, London, UK Oliver J. Bower, Afshan McCarthy & Kathy K. Niakan MRC Laboratory of Molecular Biology, Cambridge, UK Kashish Singh Assisted Reproduction and Gynaecology Centre, London, UK Patricia Garcia, Valerie Shaikly & Mohamed Taranissi Create Fertility, London, UK Martin Wilding Centre for Reproductive and Genetic Health, London, United Kingdom Paul Serhal, Rabi A. Odia & Mina Vasilic Newcastle Fertility Centre, Newcastle upon Tyne Hospitals NHS Trust, Biosciences Institute, Newcastle University Centre for Life, Newcastle upon Tyne, UK Meenakshi Choudhary & Mary Herbert Bourn Hall Clinic, Bourn, UK Athanasios Papathanasiou, Kay Elder, Phil Snell & Leila Christie Rosamund Stone Zander Translational Neuroscience Center, Boston Children’s Hospital, Boston, MA, USA Mandana Arbab Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children’s Hosptial, Harvard Medical School, Boston, MA, USA Mandana Arbab Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA, USA Mandana Arbab & David R. …