‘Megacluster’ of genes enables bacteria to make potent antibiotic mixture

Antimicrobial Resistance Collaborators. Lancet 399 , 629–655 (2022). Article PubMed Google Scholar Ling, L. L. et al. Nature 517 , 455–459 (2015). Article PubMed Google Scholar Imai, Y. et al. Nature 576 , 459–464 (2019). Article PubMed Google Scholar Wang, Z. et al. Nature 601 , 606–611 (2022). Article PubMed Google Scholar Hover, B. M. et al. Nature Microbiol. 3 , 415–422 (2018). Article PubMed Google Scholar Smith, P. A. et al. Nature 561 , 189–194 (2018). Article PubMed Google Scholar Wan, F., Torres, M. D. T., Peng, J. & de la Fuente-Nunez, C. Nature Biomed. Eng. 8 , 854–871 (2024). Article PubMed Google Scholar Gordzevich, R. et al. Nature https://doi.org/10.1038/s41586-026-10647-9 (2026). Article Google Scholar Atanasov, A. G. et al. Nature Rev. Drug Discov. 20 , 200–216 (2021). Article PubMed Google Scholar Zlitni, S., Ferruccio, L. F. & Brown, E. D. Nature Chem. Biol. 9 , 796–804 (2013). Article PubMed Google Scholar Carfrae, L. A. et al. Nature Microbiol. 5 , 93–101 (2020). Article PubMed Google Scholar Meyer, K. J. & Nodwell, J. R. Nature Microbiol. 6 , 1118–1128 (2021). Article PubMed Google Scholar Blaskovich, M. A. T. & Cooper, M. A. npj Antimicrob. Resist. 3 , 47 (2025). Article PubMed Google Scholar