A mosaic of whole-body representations on the human precentral gyrus

Experimental procedures Study participants This study includes data from eight participants who each gave informed consent before any experimental procedures. Participants T5, T11, T12, T15, T16 and T17 were enrolled in the BrainGate2 Neural Interface System clinical trial (ClinicalTrials.gov Identifier: NCT00912041 , registered 3 June 2009), and represent all BrainGate2 participants who were enrolled at the time the data were collected and analysed. This pilot clinical trial was approved under an Investigational Device Exemption (IDE) by the US Food and Drug Administration (FDA; Investigational Device Exemption #G090003). Permission was also granted by the Stanford University Institutional Review Board (IRB; protocol #20804), the Mass General Brigham IRB (protocol #2009P000505), the University of California, Davis IRB (protocol #1843264), the Emory University IRB (protocol #00003070) and the Providence VA Healthcare IRB. Participants C1 and C2 were enrolled under a separate multi-site clinical trial (ClinicalTrials.gov Identifier: NCT01894802 , registered 10 July 2013), which was also conducted under an IDE from the US FDA and approved by the IRBs at the University of Pittsburgh and the University of Chicago. C1 and C2 represent all participants enrolled under NCT01894802 who were available at the time of data collection to participate in this study, given competing demands on participant time for other research goals. …