SIRT7 regulates dosage compensation and safeguards the female X chromosome

Nature News ·

SIRT7 regulates dosage compensation and safeguards the female X chromosome

Vaquero, A. The conserved role of sirtuins in chromatin regulation. Int. J. Dev. Biol. 53 , 303–322 (2009). Article CAS PubMed Google Scholar Giblin, W., Skinner, M. E. & Lombard, D. B. …

Vaquero, A. The conserved role of sirtuins in chromatin regulation. Int. J. Dev. Biol. 53 , 303–322 (2009). Article CAS PubMed Google Scholar Giblin, W., Skinner, M. E. & Lombard, D. B. Sirtuins: guardians of mammalian healthspan. Trends Genet. 30 , 271–286 (2014). Article CAS PubMed Central PubMed Google Scholar Kim, H.-S. et al. SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. Cancer Cell 17 , 41–52 (2010). …

Original source: Nature News