Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding

These authors contributed equally: Zhiyuan Cheng, Huadong Chen, Zhaojun Wang Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA Jingkun Zeng, Zhiyuan Cheng, Zhaojun Wang, Arushi Singhal, Wayne Ngo, Daniel Rosas-Rivera & Jennifer A. Doudna Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA Jingkun Zeng, Zhiyuan Cheng, Zhaojun Wang, Arushi Singhal, Wayne Ngo, Daniel Rosas-Rivera & Jennifer A. Doudna Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA Jingkun Zeng, Hesong Han, Wayne Ngo, Chenglong Xia, Zeyuan Zhang, Min Hyung Kang, Niren Murthy & Jennifer A. Doudna Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA Jennifer A. Doudna Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA Jennifer A. Doudna Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA Jennifer A. Doudna California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA Jingkun Zeng, Wayne Ngo, Zeyuan Zhang & Jennifer A. Doudna Li Ka Shing Center for Genomic Engineering, University of California, Berkeley, Berkeley, CA, USA Jennifer A. Doudna Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA Jennifer A. …