Design of one-component quasisymmetric protein nanocages

Hsia, Y. et al. Design of a hyperstable 60-subunit protein icosahedron. Nature 535 , 136–139 (2016). Article ADS CAS PubMed PubMed Central Google Scholar Caspar, D. L. D. & Klug, A. Physical principles in the construction of regular viruses. Cold Spring Harb. Symp. Quant. Biol. 27 , 1–24 (1962). Article CAS PubMed Google Scholar Rayment, I., Baker, T. S., Caspar, D. L. D. & Murakami, W. T. Polyoma virus capsid structure at 22.5 Å resolution. Nature 295 , 110–115 (1982). Article ADS CAS PubMed PubMed Central Google Scholar Liddington, R. C. et al. Structure of simian virus 40 at 3.8-Å resolution. Nature 354 , 278–284 (1991). Article ADS CAS PubMed Google Scholar Prasad, B. V. V. et al. X-ray crystallographic structure of the Norwalk virus capsid. Science 286 , 287–290 (1999). Article ADS CAS PubMed Google Scholar Abad-Zapatero, C. et al. Structure of southern bean mosaic virus at 2.8 Å resolution. Nature 286 , 33–39 (1980). Article ADS CAS PubMed Google Scholar Harrison, S. C., Olson, A. J., Schutt, C. E., Winkler, F. K. & Bricogne, G. Tomato bushy stunt virus at 2.9 Å resolution. Nature 276 , 368–373 (1978). Article ADS CAS PubMed Google Scholar Lee, S. et al. Four-component protein nanocages designed by programmed symmetry breaking. Nature 638 , 546–552 (2025). Article ADS CAS PubMed Google Scholar Dowling, Q. M. et al. Hierarchical design of pseudosymmetric protein nanocages. Nature 638 , 553–561 (2025). Article ADS CAS PubMed Google Scholar Xia, X. et al. …