Feature-specific threat coding in lateral septum guides defensive action
Nature News ·

Risold, P. Y. & Swanson, L. W. Connections of the rat lateral septal complex. Brain Res. Rev. 24 , 115–195 (1997). Article CAS PubMed Google Scholar Besnard, A. & Leroy, F. …
Risold, P. Y. & Swanson, L. W. Connections of the rat lateral septal complex. Brain Res. Rev. 24 , 115–195 (1997). Article CAS PubMed Google Scholar Besnard, A. & Leroy, F. Top-down regulation of motivated behaviors via lateral septum sub-circuits. Mol. Psychiatry 27 , 3119–3128 (2022). Article PubMed Google Scholar Risold, P. Y. & Swanson, L. W. Chemoarchitecture of the rat lateral septal nucleus1Published on the World Wide Web on 2 June 1997.1. Brain Res. Rev. 24 , 91–113 (1997). Article CAS PubMed Google Scholar Franklin, T. B., Saab, B. J. & Mansuy, I. M. Neural mechanisms of stress resilience and vulnerability. Neuron 75 , 747–761 (2012). Article CAS PubMed Google Scholar Henckens, M. J. A. G., Deussing, J. M. & Chen, A. Region-specific roles of the corticotropin-releasing factor–urocortin system in stress. Nat. Rev. Neurosci. 17 , 636–651 (2016). Article CAS PubMed Google Scholar Anthony, T. E. et al. Control of stress-induced persistent anxiety by an extra-amygdala septohypothalamic circuit. Cell 156 , 522–536 (2014). Article CAS PubMed PubMed Central Google Scholar Hashimoto, M. et al. Lateral septum modulates cortical state to tune responsivity to threat stimuli. Cell Rep. 41 , 111521 (2022). Article CAS PubMed PubMed Central Google Scholar Sheehan, T. P., Chambers, R. A. & Russell, D. S. Regulation of affect by the lateral septum: implications for neuropsychiatry. Brain Res. Rev. 46 , 71–117 (2004). Article PubMed Google Scholar Albert, D. J. & Chew, G. L. …
Original source: Nature News