Genetic analysis of circulating metabolic traits in 619,372 individuals
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Suzuki, K. et al. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature 627 , 347–357 (2024). Article ADS CAS PubMed PubMed Central Google Scholar Zhou, W. et al. …
Suzuki, K. et al. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature 627 , 347–357 (2024). Article ADS CAS PubMed PubMed Central Google Scholar Zhou, W. et al. Global Biobank Meta-analysis Initiative: powering genetic discovery across human disease. Cell Genom. 2 , 100192 (2022). Article CAS PubMed PubMed Central Google Scholar Yengo, L. et al. A saturated map of common genetic variants associated with human height. Nature 610 , 704–712 (2022). Article ADS CAS PubMed PubMed Central Google Scholar COVID-19 Host Genetics Initiative A second update on mapping the human genetic architecture of COVID-19. Nature 621 , E7–E26 (2023). Article Google Scholar Aragam, K. G. et al. Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants. Nat. Genet. 54 , 1803–1815 (2022). Article CAS PubMed PubMed Central Google Scholar Lotta, L. A. et al. Genetic predisposition to an impaired metabolism of the branched-chain amino acids and risk of type 2 diabetes: a Mendelian randomisation analysis. PLoS Med. 13 , e1002179 (2016). Article PubMed PubMed Central Google Scholar Vanweert, F., Schrauwen, P. & Phielix, E. Role of branched-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCAA metabolism in type 2 diabetes. Nutr. Diabetes 12 , 35 (2022). Article CAS PubMed PubMed Central Google Scholar Karjalainen, M. K. et al. …
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