Genetic survey exposes flaws in widely used mouse models

C57BL/6 mice, such as the one pictured here, are commonly used in animal research. Credit: Dani Maver/Alamy Half of laboratory mice are not what scientists think they are, a genetic analysis of hundreds of strains that are distributed globally for animal research has found. The study, published today in Science 1 , uncovered widespread inconsistencies between the reported names of mouse strains and their actual genetic makeup. …