Steric hindrance of antibody binding in an Omicron spike fusion intermediate

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Steric hindrance of antibody binding in an Omicron spike fusion intermediate

Low, J. S. et al. ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies. Science 377 , 735–741 (2022). ADS CAS PubMed PubMed Central Google Scholar Sun, X. …

Low, J. S. et al. ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies. Science 377 , 735–741 (2022). ADS CAS PubMed PubMed Central Google Scholar Sun, X. et al. Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2. Nat. Microbiol. 7 , 1063–1074 (2022). CAS PubMed Google Scholar Qu, P. K. et al. Enhanced neutralization resistance of SARS-CoV-2 Omicron subvariants BQ.1, BQ.1.1, BA.4.6, BF.7, and BA.2.75.2. …

Original source: Nature News